anti-human CCR D6
$345.00
Amount: 200 ug
Synonyms: CCR D6; D6; Beta Chemokine Receptor D6
Specifications
Host Species: Goat
Antigen: Synthetic peptide C-LATEDADSENSSFYYYDYLDEVAFML corresponding to the N-terminal extracellular domain of human D6
Reactive Species: Human, Mouse not tested
Format/Conjugates/Purification: Affinity Purified
Buffer & Formulation: Affinity purified antibody in 10 mM KHPO4, 140 mM NaCl, BSA @ 1mg/ml and 0.1 % sodium azide
Storage: Aliquot and freeze at -20° C. Avoid freeze-thaw cycles.
Clone: Polyclonal
Applications
ELISA: 1:50,000
Western Blotting: 1:500
IHC: 1:125
Flow Cytometry: 2-6ul/10^6cells/50-100ul
References
Bradford L, Marshall H, Robertson H, Kirby JA, Graham G, Ali S, O’Boyle G. Cardiac allograft rejection: examination of the expression and function of the decoy chemokine receptor D6. Transplantation. 2010 Jun 15;89(11):1411-6. Abstract
Neil SJ, Aasa-Chapman MM, Clapham PR, Nibbs RJ, McKnight A, Weiss RA. The promiscuous CC chemokine receptor D6 is a functional coreceptor for primary isolates of human immunodeficiency virus type 1 (HIV-1) and HIV-2 on astrocytes. J Virol. 2005 Aug;79(15):9618-24. Full Text FC
Comments
Peptide sequence is < 50 % identical to other chemokine receptors in this region and cross-reactivity to mouse D6 was not tested. Product CI0171 is biotin conjugated.