Capralogics, Inc., P.O. Box 356, Hardwick, MA 01037 USA
Phone (800) 975-6866 / (413) 477-6866 • FAX (413) 643-0067 • capralogics.com

Beta Chemokine Receptor D6 (human) Biotin Conjugated IgG

$325.00

SKU: CI0171

Synonyms:

CCR D6; D6; Beta Chemokine Receptor D6

CI0171: Immunohistochemistry with CCR D6 Biotin Conjugate antibody to human Chemokine Receptor D6 on paraffin sections of human spleen.

Specifications

Amount:

100 ug

Host Species:

Goat

Antigen:

Synthetic peptide C-LATEDADSENSSFYYYDYLDEVAFML corresponding to the N-terminal extracellular domain of human D6

Reactive Species:

Human

Format/Conjugates/Purification:

Peptide Affinity Purification

Buffer & Formulation:

10 mM KHPO4, 140 mM NaCl, BSA @ 1mg/ml and 0.1 % sodium azide. pH 7.2

Storage:

Aliquot and freeze at -80° C. Stable for 3 years when stored at -80C. Avoid freeze-thaw cycles.

Clone:

Polyclonal

Applications

ELISA:

1:100000

Western Blotting:

2 ug/ml

IHC:

8 ug/ml

Comments:

Peptide sequence is < 50 % identical to other chemokine receptors in this region and cross-reactivity to mouse D6 was not tested.

Unconjugated version of this antibody is acceptable for Flow Cytometry.

Quality Control: Immunohistochemistry on human spleen.

References:

Neil SJ, Aasa-Chapman MM, Clapham PR, Nibbs RJ, McKnight A, Weiss RA. The promiscuous CC chemokine receptor D6 is a functional coreceptor for primary isolates of human immunodeficiency virus type 1 (HIV-1) and HIV-2 on astrocytes. J Virol. 2005 Aug;79(15):9618-24. Full Text FC

Nibbs RJB et al. Cloning and characterzation of a novel promiscuous human beta-chemokine receptor D6 J Biol. Chem. 1997, vol 272: 32078-83

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Beta Chemokine Receptor D6 (human) Biotin Conjugated IgG

Specifications

Applications

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