Beta Chemokine Receptor D6 (human) Biotin Conjugated IgG
$345.00
Amount: 100 ug
Synonyms: CCR D6; D6; Beta Chemokine Receptor D6
Specifications
Host Species: Goat
Antigen: Synthetic peptide C-LATEDADSENSSFYYYDYLDEVAFML corresponding to the N-terminal extracellular domain of human D6
Reactive Species: Human
Format/Conjugates/Purification: Peptide Affinity Purification
Buffer & Formulation: 10 mM KHPO4, 140 mM NaCl, BSA @ 1mg/ml and 0.1 % sodium azide. pH 7.2
Storage: Aliquot and freeze at -80° C. Stable for 3 years when stored at -80C. Avoid freeze-thaw cycles.
Clone: Polyclonal
Applications
ELISA: 1:100000
Western Blotting: 2 ug/ml
IHC: 8 ug/ml
References
Neil SJ, Aasa-Chapman MM, Clapham PR, Nibbs RJ, McKnight A, Weiss RA. The promiscuous CC chemokine receptor D6 is a functional coreceptor for primary isolates of human immunodeficiency virus type 1 (HIV-1) and HIV-2 on astrocytes. J Virol. 2005 Aug;79(15):9618-24. Full Text FC
Nibbs RJB et al. Cloning and characterzation of a novel promiscuous human beta-chemokine receptor D6 J Biol. Chem. 1997, vol 272: 32078-83
Comments
Peptide sequence is < 50 % identical to other chemokine receptors in this region and cross-reactivity to mouse D6 was not tested.
Unconjugated version of this antibody is acceptable for Flow Cytometry.
Quality Control: Immunohistochemistry on human spleen.