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anti-mouse CXCR4

$345.00

SKU: CI0116 Category:

Amount: 200 ug

Synonyms: Stromal cell-derived factor 1 receptor (SDF-1 receptor), Fusin, Leukocyte-derived seven transmembrane domain receptor (LESTR), Pre-B-cell-derived chemokine receptor (PB-CKR), and CD184 antigen

Specifications

Host Species: Goat

Antigen: YSEEVGSGDYDSNKEPCFRDENVHFNR corresponding to the N-terminal extracellular domain of mouse CXCR4 receptor

Reactive Species: Human, Mouse

Buffer & Formulation: Affinity purified antibody in 10 mM KHPO4, 140 mM NaCl, BSA @ 1mg/ml and 0.1 % sodium azide

Storage: Aliquot and freeze at -20° C. Avoid freeze-thaw cycles.

Clone: Polyclonal

Applications

ELISA: 1:25,000

Western Blotting: 1:500

IHC: 1:150

Comments

This antibody binds to CXCR4 receptor on mouse spleen leukocytes as determined by immunocytochemistry.

References

Lima E Silva R, Shen J, Hackett SF, Kachi S, Akiyama H, Kiuchi K, Yokoi K, Hatara MC, Lauer T, Aslam S, Gong YY, Xiao WH, Khu NH, Thut C, Campochiaro PA.  The SDF-1/CXCR4 ligand/receptor pair is an important contributor to several types of ocular neovascularization.  FASEB J. 2007 May 23; Epub ahead of print Abstract IH
Schabath H, Runz S, Joumaa S, Altevogt P.  CD24 affects CXCR4 function in pre-B lymphocytes and breast carcinoma cells.  J Cell Sci. 2006 Jan 15;119(Pt 2):314-25.  Full Text WB
Belmadani A, Tran PB, Ren D, Assimacopoulos S, Grove EA, Miller RJ.  The chemokine stromal cell-derived factor-1 regulates the migration of sensory neuron progenitors.  J Neurosci. 2005 Apr 20;25(16):3995-4003  Full Text IH
Busso N, Wagtmann N, Herling C, Chobaz-Peclat V, Bischof-Delaloye A, So A, Grouzmann E. Circulating CD26 is negatively associated with inflammation in human and experimental arthritis.  Am J Pathol.  2005 Feb;166(2):433-42.   Full Text IH
Nishiumi F, Komiya T, Ikenishi K.  The mode and molecular mechanisms of the migration of presumptive PGC in the endoderm cell mass of Xenopus embryos.  Dev Growth Differ. 2005 Jan;47(1):37-48  Abstract IH
Tran PB, Ren D, Veldhouse TJ, Miller RJ.  Chemokine receptors are expressed widely by embryonic and adult neural progenitor cells.  J Neurosci Res. 2004 Apr 1;76(1):20-34  Abstract IH
Kayali AG, Van Gunst K, Campbell IL, Stotland A, Kritzik M, Liu G, Flodstrom-Tullberg M, Zhang YQ, Sarvetnick N. The stromal cell-derived factor-1alpha/CXCR4 ligand-receptor axis is critical for progenitor survival and migration in the pancreas. J Cell Biol. 2003 Nov 24;163(4):859-69 Full TextIH

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