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anti-human CXCR4

$345.00

SKU: CI0115 Category:

Amount: 200 ug

Synonyms: Stromal cell-derived factor 1 receptor (SDF-1 receptor), Fusin, Leukocyte-derived seven transmembrane domain receptor (LESTR), LCR1, FB22, NPYRL, HM89, and CD184 antigen

Specifications

Host Species: Goat

Antigen: Synthetic peptide TEEMGSGDYDSMKEPCFREENANFNKC corresponding to N-terminal extracellular domain of human CXCR4 receptor

Reactive Species: Human, Rat

Format/Conjugates/Purification: Peptide Affinity Purification

Buffer & Formulation: Peptide Affinity purified antibody @ 1mg/ml in 10 mM KHPO4, 140 mM NaCl, BSA @ 1 mg/ml with 0.1 % sodium azide

Storage: Aliquot and freeze at -20° C. Avoid freeze-thaw cycles.

Clone: Polyclonal

Applications

ELISA: 1:25,000

Western Blotting: 1:250

IHC: 1:150

References

Lollert A, Junginger T, Schimanski CC, Biesterfeld S, Gockel I, Düber C, Oberholzer K. Rectal cancer: Dynamic contrast-enhanced MRI correlates with lymph node status and epidermal growth factor receptor expression. J Magn Reson Imaging. 2013 Oct 11. Abstract IH

Fukunaga S, Maeda K, Noda E, Inoue T, Wada K, Hirakawa K. Association between Expression of Vascular Endothelial Growth Factor C, Chemokine Receptor CXCR4 and Lymph Node Metastasis in Colorectal Cancer.  Oncology. 2007 Jul 19;71(3-4):204-211  Abstract IH

Wehler T, Wolfert F, Schimanski CC, Gockel I, Herr W, Biesterfeld S, Seifert JK, Adwan H, Berger MR, Junginger T, Galle PR, Moehler M.  Strong expression of chemokine receptor CXCR4 by pancreatic cancer correlates with advanced disease.  Oncol Rep. 2006 Dec;16(6):1159-64.  Abstract IH
Gockel I, Schimanski CC, Heinrich C, Wehler T, Frerichs K, Drescher D, von Langsdorff C, Domeyer M, Biesterfeld S, Galle PR, Junginger T, Moehler M. BMC Cancer.  Expression of chemokine receptor CXCR4 in esophageal squamous cell and adenocarcinoma.  2006 Dec 18;6:290.  Full Text IH
Schimanski CC, Bahre R, Gockel I, Muller A, Frerichs K, Horner V, Teufel A, Simiantonaki N, Biesterfeld S, Wehler T, Schuler M, Achenbach T, Junginger T, Galle PR, Moehler M.  Dissemination of hepatocellular carcinoma is mediated via chemokine receptor CXCR4.  Br J Cancer. 2006 Jul 17;95(2):210-7.   Abstract IH
Schimanski CC, Schwald S, Simiantonaki N, Jayasinghe C, Gonner U, Wilsberg V, Junginger T, Berger MR, Galle PR, Moehler M. Effect of chemokine receptors CXCR4 and CCR7 on the metastatic behavior of human colorectal cancer. Clin Cancer Res. 2005 Mar 1;11(5):1743-50  Abstract IH

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