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anti-human CCR8 N-terminal

$345.00

SKU: CI0120 Category:

Amount: 200 ug

Synonyms: C-C chemokine receptor type 8, CC-CKR-8, CCR-8, GPR-CY6, Chemokine receptor-like 1, CKR-L1, TER1, CMKBRL2, CC-chemokine receptor CHEMR1, and CDw198 antigen

Specifications

Host Species: Goat

Antigen: Synthetic peptide VTDYYYPDIFSSPCDAELIQTNGKL-C corresponding to aa 12-36 of human CCR8

Reactive Species: Human, Mouse, Not tested

Format/Conjugates/Purification: Affinity Purification

Buffer & Formulation: Affinity purified antibody in 10 mM KHPO4, 140 mM NaCl, BSA @ 1mg/ml and 0.1 % sodium azide

Storage: Aliquot and freeze at -20° C. Avoid freeze-thaw cycles.

Clone: Polyclonal

Applications

ELISA: 1:50,000

Western Blotting: 1:500

IHC: 1:125

Flow Cytometry: 2-6ul/10^6cells/50-100ul

References

Faaij CM, Lankester AC, Spierings E, Hoogeboom M, Bowman EP, Bierings M, Révész T, Egeler RM, van Tol MJ, Annels NE.  A possible role for CCL27/CTACK-CCR10 interaction in recruiting CD4 T cells to skin in human graft-versus-host disease. Br J Haematol. 2006 Jun;133(5):538-49.  Abstract FC
Muller A, Sonkoly E, Eulert C, Gerber PA, Kubitza R, Schirlau K, Franken-Kunkel P, Poremba C, Snyderman C, Klotz LO, Ruzicka T, Bier H, Zlotnik A, Whiteside TL, Homey B, Hoffmann TK.  Chemokine receptors in head and neck cancer: association with metastatic spread and regulation during chemotherapy.  Int J Cancer. 2006 May 1;118(9):2147-57.  Abstract FC
Gombert M, Dieu-Nosjean MC, Winterberg F, Bunemann E, Kubitza RC, Da Cunha L, Haahtela A, Lehtimaki S, Muller A, Rieker J, Meller S, Pivarcsi A, Koreck A, Fridman WH, Zentgraf HW, Pavenstadt H, Amara A, Caux C, Kemeny L, Alenius H, Lauerma A, Ruzicka T, Zlotnik A, Homey B.  CCL1-CCR8 interactions: an axis mediating the recruitment of T cells and Langerhans-type dendritic cells to sites of atopic skin inflammation.  J Immunol.  2005 Apr 15;174(8):5082-91.  Full Text FC
Annels NE, Willemze AJ, van der Velden VH, Faaij CM, van Wering E, Sie-Go DM, Egeler RM, van Tol MJ, Revesz T. Possible link between unique chemokine and homing receptor expression at diagnosis and relapse location in a patient with childhood T-ALL. Blood. 2004 Apr 1;103(7):2806-8 Full Text FC
Strasly M, Doronzo G, Capello P, Valdembri D, Arese M, Mitola S, Moore P, Alessandri G, Giovarelli M, Bussolino F.  CCL16 activates an angiogenic program in vascular endothelial cells.  Blood. 2004 Jan 1;103(1):40-9.  Full Text N
Haque NS, Fallon JT, Taubman MB, Harpel PC. The chemokine receptor CCR8 mediates human endothelial cell chemotaxis induced by I-309 and Kaposi sarcoma herpesvirus-encoded vMIP-I and by lipoprotein(a)-stimulated endothelial cell conditioned medium. Blood. 2001 Jan 1;97(1):39-45.  Full Text N

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