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anti-human CCR8 2nd extracellular domain

$345.00

SKU: CI0121 Category:

Amount: 100 ug

Synonyms: C-C chemokine receptor type 8, CC-CKR-8, CCR-8, GPR-CY6, Chemokine receptor-like 1, CKR-L1, TER1, CMKBRL2, CC-chemokine receptor CHEMR1, and CDw198 antigen

Specifications

Host Species: Goat

Antigen: Synthetic peptide C-183YSFYNQQTLK193 corresponding to the 2nd extracellular domain sequence of human CCR8

Reactive Species: Human

Format/Conjugates/Purification: Affinity Purification

Buffer & Formulation: Affinity purified antibody in 10 mM KHPO4, 140 mM NaCl, BSA @ 1mg/ml and 0.1 % sodium azide, pH 7.2

Storage: Aliquot and freeze at -20° C. Avoid freeze-thaw cycles.

Clone: Polyclonal

Applications

ELISA: 1:35,000

Western Blotting: 1:1000

IHC: 1:150

References

Trebst C, Staugaitis SM, Kivisakk P, Mahad D, Cathcart MK, Tucky B, Wei T, Rani MR, Horuk R, Aldape KD, Pardo CA, Lucchinetti CF, Lassmann H, Ransohoff RM.  CC chemokine receptor 8 in the central nervous system is associated with phagocytic macrophages.  Am J Pathol. 2003 Feb;162(2):427-38.  Article IH
Iellem A, Mariani M, Lang R, Recalde H, Panina-Bordignon P, Sinigaglia F, D’Ambrosio D.  Unique chemotactic response profile and specific expression of chemokine receptors CCR4 and CCR8 by CD4(+)CD25(+) regulatory T cells. J Exp Med. 2001 Sep 17;194(6):847-53.  Article IH

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