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anti-human CCR4

$345.00

SKU: CI0117 Category:

Amount: 200 ug

Synonyms: C-C CKR-4, CC-CKR-4, CCR-4 and K5-5 and is 85% identical to murine CCR4 receptor

Specifications

Host Species: Goat

Antigen: 17SNYYLYESIPKPCTKEGIKAFGE39 corresponding to human CCR4 extracellular domain

Reactive Species: Human, Monkey, Mouse, Not tested

Format/Conjugates/Purification: Affinity Purification

Buffer & Formulation: Affinity purified antibody in 10 mM KHPO4, 140 mM NaCl, BSA @ 1mg/ml and 0.1 % sodium azide

Storage: Aliquot and freeze at -20° C. Avoid freeze-thaw cycles.

Clone: Polyclonal

Applications

ELISA: 1:30,000

Western Blotting: 1:500

IHC: 1:200

Flow Cytometry: 1:12

Comments

Human spleen

References

Yagi H, Seo N, Ohshima A, Itoh T, Itoh N, Horibe T, Yoshinari Y, Takigawa M, Hashizume H.  Chemokine Receptor Expression in Cutaneous T cell and NK/T-cell Lymphomas: Immunohistochemical Staining and In Vitro Chemotactic Assay.  Am J Surg Pathol. 2006 Sep;30(9):1111-9.  Abstract IH
Ritter M, Goggel R, Chaudhary N, Wiedenmann A, Jung B, Weith A, Seither P. Elevated expression of TARC (CCL17) and MDC (CCL22) in models of cigarette smoke-induced pulmonary inflammation.  Biochem Biophys Res Commun. 2005 Aug 19;334(1):254-62. Abstract IH
Luttichaux IV, Notohamiprodjo M, Wechselberger A, Peters C, Henger A, Seliger C, Djafarzadeh R, Huss R, Nelson PJ.  Human Adult CD34() Progenitor Cells Functionally Express the Chemokine Receptors CCR1, CCR4, CCR7, CXCR5, and CCR10 but Not CXCR4. Stem Cells Dev. 2005 Jun;14(3):329-36 Abstract FC
Shadidi KR, Aarvak T, Henriksen JE, Natvig JB, Thompson KM.The chemokines CCL5, CCL2 and CXCL12 play significant roles in the migration of Th1 cells into rheumatoid synovial tissue. Scand J Immunol. 2003 Feb;57(2):192-8 Abstract IC

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