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anti-human CCR10

$345.00

SKU: CI0126 Category:

Amount: 200 ug

Synonyms: C-C CKR-10, CC-CKR-10, CCR-10, and G-protein coupled receptor 2

Specifications

Host Species: Goat

Antigen: Synthetic peptide VSWGHYSGDEEDAYSAEPLPELC corresponding to amino acids 9-31 of human CCR10

Reactive Species: Human, Mouse not tested

Format/Conjugates/Purification: Affinity Purified

Buffer & Formulation: 10 mM KHPO4, 140 mM NaCl with 1 mg/ml BSA and 0.1 % sodium azide

Storage: Aliquot and freeze at -20° C. Avoid freeze-thaw cycles.

Clone: Polyclonal

Applications

ELISA: 1:37,500

Western Blotting: 1:500

IHC: 1:125

Flow Cytometry: 1:12

References

Kai H, Kadono T, Kakinuma T, Tomita M, Ohmatsu H, Asano Y, Tada Y, Sugaya M, Sato S. CCR10 and CCL27 are overexpressed in cutaneous squamous cell carcinoma. Pathol Res Pract. 2011 Jan 15;207(1):43-8 Abstract IH
Castelletti E, Lo Caputo S, Kuhn L, Borelli M, Gajardo J, Sinkala M, Trabattoni D, Kankasa C, Lauri E, Clivio A, Piacentini L, Bray DH, Aldrovandi GM, Thea DM, Veas F, Nebuloni M, Mazzotta F, Clerici M. The Mucosae-Associated Epithelial Chemokine (MEC/CCL28) Modulates Immunity in HIV Infection.  PLoS ONE. 2007 Oct 3;2(10):e969.  Full Text FC
Eksteen B, Miles A, Curbishley SM, Tselepis C, Grant AJ, Walker LS, Adams DH.  Epithelial inflammation is associated with CCL28 production and the recruitment of regulatory T cells expressing CCR10.  J Immunol. 2006 Jul 1;177(1):593-603.  Full Text FC
Luttichaux IV, Notohamiprodjo M, Wechselberger A, Peters C, Henger A, Seliger C, Djafarzadeh R, Huss R, Nelson PJ.  Human Adult CD34() Progenitor Cells Functionally Express the Chemokine Receptors CCR1, CCR4, CCR7, CXCR5, and CCR10 but Not CXCR4. Stem Cells Dev 2005 Jun;14(3):329-36 Abstract FC
Notohamiprodjo M, Segerer S, Huss R, Hildebrandt B, Soler D, Djafarzadeh R, Buck W, Nelson PJ, von Luettichau I.  CCR10 is expressed in cutaneous T-cell lymphoma.  Int J Cancer. 2005 Jul 1;115(4):641-7.  Abstract FC
Hislop AD, Kuo M, Drake-Lee AB, Akbar AN, Bergler W, Hammerschmitt N, Khan N, Palendira U, Leese AM, Timms JM, Bell AI, Buckley CD, Rickinson AB.  Tonsillar homing of Epstein-Barr virus-specific CD8+ T cells and the virus-host balance.  J Clin Invest. 2005 Sep;115(9):2546-55.  Full Text FC
Hirata T, Furukawa Y, Yang BG, Hieshima K, Fukuda M, Kannagi R, Yoshie O, Miyasaka M. Human P-selectin glycoprotein ligand-1 (PSGL-1) interacts with the skin-associated chemokine CCL27 via sulfated tyrosines at the PSGL-1 amino terminus. J Biol Chem. 2004 Dec 10;279(50):51775-82.  Full Text FC
Murakami T, Cardones AR, Finkelstein SE, Restifo NP, Klaunberg BA, Nestle FO, Castillo SS, Dennis PA, Hwang ST. Immune evasion by murine melanoma mediated through CC chemokine receptor-10. J Exp Med. 2003 Nov 3;198(9):1337-47. Full text IH, WB

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