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human ADPR2 C-terminus2 aa321-342

$345.00

SKU: CI0170 Category:

Amount: 200 ug

Synonyms: Human Adiponectin Receptor 2, ADPR2

Specifications

Host Species: Goat

Antigen: Synthetic peptide (HFHGVSNLQEFRFMIGGGC) corresponding to aa 321-342 of the C-terminal domain of Human, Mouse, Macaca and Rat ADPR 2 Receptor

Reactive Species: Human, Mouse, Macaque, Rat

Format/Conjugates/Purification: Affinity Purification

Buffer & Formulation: Liquid. 200 ug of peptide affinity purified IgG in PBS (pH 7.2) at 1.0mg/ml with 1 mg/ml BSA and 0.1% sodium azide

Storage: Freeze at -80 °C. Stable for at least 3 years when stored at -80 °C.

Clone: Polyclonal

Applications

Western Blotting: 1: 1,000

IHC: 1: 250

Comments

Recognizes Human, Rat, Mouse and Macaca ADPR2 Receptor.  Likely to cross-react to ADPR1 Receptor.  May be used in developing sandwich ELISA assays in combination with antibodies specific to N-Terminus of ADPR2 Receptor

ADPR2 aa 321-342 sequence similarity between several species and Human ADPR1:
YITGAALYAARIPERFFPGKC  321-342 ADPR2 Human
YITGAALYAARIPERFFPGKC  321-342 ADPR2 Rat 
YITGAALYAARIPERFFPGKC  321-342 ADPR2 Mouse
YITGAALYAARIPERFFPGKC  321-342 ADPR2 Macaca
YITGAALYAARIPERFFPGKC  320-341 MGC85478[Xenopus laevis]
YITGAGLYAARIPERFFPGKC  310-329 Human ADPR1

References

Yamauchi,T. et.al , Cloning of adiponectin receptors that mediate antidiabetic metabolic effects
Nature 423 (6941), 762-769 (2003)    Abstract

Staiger,H. et.al,  Expression of adiponectin receptor mRNA in human skeletal muscle cells is related to in vivo parameters of glucose and lipid metabolism.  Diabetes 53 (9), 2195-2201 (2004)   Abstract

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