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Human (and Mouse) ADPR1 C-terminus aa317-340

$345.00

SKU: CI0168 Category:

Amount: 200 ug

Synonyms: Adiponectin Receptor 1, ADPR1

Specifications

Host Species: Goat

Antigen: Synthetic peptide (CYAARIPERFFPGKFDIWFQSHQIF) corresponding to aa 317-340 of the C-terminal domain of Human, Mouse and Rat ADPR 1 Receptor

Reactive Species: Human, Mouse

Format/Conjugates/Purification: Affinity Purification

Buffer & Formulation: Liquid. 200 ug of peptide affinity purified IgG in PBS at 1.0mg/ml with 1 mg/ml BSA and 0.1% sodium azide.

Storage: Freeze at -80 °C. Stable for at least 3 years when stored at -80 °C.

Clone: Polyclonal

Applications

Western Blotting: 1:1,000

IHC: 1:250

Comments

Recognizes Human ADPR1 Receptor. Peptide sequence is <50% identical to other receptors in this region. Cross reacts to Rat and Mouse ADPR1 Receptors. Not likely to cross-react to ADPR2.

The peptide sequence used is identical for aa 317-340 between human, mouse and rat:
YAARIPERFFPGKFDIWFQSHQIF  317-340 ADPR1 Human
YAARIPERFFPGKFDIWFQSHQIF  317-340 ADPR1 Rat 
YAARIPERFFPGKFDIWFQSHQIF  317-340 ADPR1 Mouse

References

Yamauchi,T. et.al , Cloning of adiponectin receptors that mediate antidiabetic metabolic effects
Nature 423 (6941), 762-769 (2003)   Abstract

Staiger,H. et.al,  Expression of adiponectin receptor mRNA in human skeletal muscle cells is related to in vivo parameters of glucose and lipid metabolism.  Diabetes 53 (9), 2195-2201 (2004)   Abstract

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