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anti-human pp36 T-cell adaptor

$345.00

SKU: CI0138 Category:

Amount: 100 ug

Synonyms: LAT

Specifications

Host Species: Rabbit

Antigen: Synthetic peptide CHRLPGSYDSTSSDSLYPRGI corresponding to amino acids 29-49 at N-terminus of human pp36, a tyrosine-phosporylated adaptor protein.

Reactive Species: Mouse

Format/Conjugates/Purification: Affinity Purified

Buffer & Formulation: Affinity purified antibody in 10 mM KHPO4, 140 mM NaCl, BSA @ 1mg/ml and 0.1 % sodium azide

Storage: Aliquot and freeze at -20° C. Avoid freeze-thaw cycles.

Clone: Polyclonal

Applications

ELISA: 1:50,000

Western Blotting: 1:500

IHC: 1:150

Comments

Western Blot:  This antibody binds to a ~40 kD protein in Western blotting on mouse lung or human T cell line Jurkat and K562 cells

References

Lindquist JA, Simeoni L, Schraven B.  Transmembrane adapters: attractants for cytoplasmic effectors.  Immunol Rev. 2003 Feb;191:165- 82.  Abstract

Weber JR et al 1998 Molecular cloning of the cDNA encoding pp36, a tyrosine-phosphorylated adaptor protein selectively expressed by T Cells and natural killer cells. J Exp Med 1998, 187, 1157-61. Full Text

 

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