At Capralogics our staff is highly trained and experienced with PBMC isolation and RNA purification from immunized animals. Large PBMC volumes are possible with llamas and alpacas with storage in your choice of media. PBMCs and RNA can also be isolated from the naive blood of non-immunized animals. Please see our Antibody Services Order Form to place an order or contact us for options.
Some PBMC Isolation Capralogics Services Citations
Alpaca PBMCs: Shapiro, Mariya B., et al. “Alpaca single B cell interrogation and heavy-chain-only antibody discovery on an optofluidic platform.” Antibody Therapeutics 6.3 (2023): 211-223. Article
Llama PBMCs: Hollingsworth, Scott A., et al. “Discovery and multimerization of cross-reactive single-domain antibodies against SARS-like viruses to enhance potency and address emerging SARS-CoV-2 variants.” Scientific Reports 13.1 (2023): 13668. Article
Alpaca PBMCs: Chen, Jin Y., et al. “A nanobody-based complement inhibitor targeting complement component 2 reduces hemolysis in a complement humanized mouse model of autoimmune hemolytic anemia.” Clinical Immunology 253 (2023): 109678. Abstract
